Imanishi Laboratory
Institute for Chemical Research, Kyoto University
About
私たちは、機能性生体分子を創製し、細胞機能や遺伝子を精密にコントロールすることを目指しています。
生命現象の深層的な理解を追求するとともに、その成果を革新的な創薬や細胞機能制御技術の開発へと繋げ、未来の生命科学・医療に貢献していきます。
Publication
KCNN4 as a genomic determinant of cytosolic delivery by the attenuated cationic lytic peptide L17E
Masashi Kuriyama, Hisaaki Hirose, Yoshimasa Kawaguchi, Junya Michibata, Masashi Maekawa, Shiroh Futaki
Mol. Ther. 33(2), 595-614 (2025)
DOI: 10.1016/j.ymthe.2024.12.050
Highly sequence-specific, timing-controllable m6 A demethylation by modulating RNA-binding affinity of m6 A erasers
Kenko Otonari, Yuri Asami, Kosuke Ogata, Yasushi Ishihama, Shiroh Futaki, Miki Imanishi
Chem.Commun. 61(1), 69-72 (2025)
DOI: 10.1039/D4CC04070H
Polysaccharide-Based Coacervate Microgel Bearing Cationic Peptides That Achieve Dynamic Cell-Membrane Structure Alteration and Facile Cytosolic Infusion of IgGs
Junya Michibata, Yoshimasa Kawaguchi, Hisaaki Hirose, Akiko Eguchi, Sayaka Deguchi, Kazuo Takayama, Wei Xu, Takuro Niidome, Yoshihiro Sasaki, Kazunari Akiyoshi, Shiroh Futaki
Bioconjug. Chem. 35(12), 1888-1899 (2024)
DOI: 10.1021/acs.bioconjchem.4c00344
